101 Questions and Answers on Influenza, written by Ab Osterhaus and David de Pooter, is a major work of reference for anyone with an interest in 'flu'. Its multilayered structure makes it easily accessible for both the interested lay person and healthcare providers who are confronted with influenza patients in their daily practice. In addition, the Q&A concept allows the reader to quickly `zap' through the information on flu as a moving target. Whenever unfamiliar medical or scientific terms appear, cross-references allow the reader to quickly acquire the necessary information. Nothing is more enjoyable than concrete cases from daily practice. That is exactly why this book is accompanied by an audio CD. In ten short tracks, Prof. Ab Osterhaus speaks about his long standing experience as a 'virus hunter', policy adviser and influenza expert. If an article in the book is marked with a symbol, this implies that the audio track with that number links up with the content of that article.