Chapter 1 IntroductionChapter 2 Efficiency and safety of ITB aftercare on locationChapter 3 Organisation of ITB troubleshootingChapter 4 Plain radiography in patients treated with intrathecal drug delivery using an implantable pump deviceChapter 5 Low-dose computed tomography with 2D/3D postprocessing as an alternative to plain radiography for intrathecal catheter visualisation: phantom pilot studyChapter 6 Catheter access port myelography in intrathecal drug deliveryChapter 7 Overview of 111Indium-DTPA scintigraphyChapter 8 Diagnostic accuracy of optimised planar-SPECT low-dose CT 111In-DTPA examinations in intrathecal drug delivery failuresChapter 9 Letter to the Editor: Isotopic scintigraphy coupled with computed tomography for the investigation of intrathecal baclofen device malfunctionChapter 10 Complications associated with intrathecal drug delivery systemsChapter 11 Restoration of cerebrospinal fluid flow to solve treatment failure caused by obstruction in long-term intrathecal bacoven administrationChapter 12 Case report: Intrathecal bacoven as an emergency treatment alleviates severe intractable autonomic dysreflexia in cervical spinal cord injuryChapter 13 General discussionThesis Erasmus University Medical Center